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Guides1/11/20265 min read

Creatine: The Most Underrated Supplement

Decades of research, proven benefits, minimal side effects. Creatine monohydrate is the most effective legal performance enhancer available.

The supplement industry is mostly nonsense. Companies selling pixie-dusted formulas with proprietary blends and exaggerated claims. But amidst the noise, one compound stands apart with actual scientific backing: creatine monohydrate.

It has been studied for over 30 years. Hundreds of peer-reviewed papers. The evidence is clear. Creatine works, it is safe, and it costs almost nothing.

The Mechanism

Your muscles store phosphocreatine, which regenerates ATP during high-intensity efforts. ATP is the energy currency for muscle contraction. When you sprint, lift, or perform any explosive movement, ATP depletes within seconds. Phosphocreatine donates its phosphate group to regenerate ATP, allowing a few more seconds of maximal effort.

Supplementing creatine increases intramuscular phosphocreatine stores by 20-40%. This means more ATP regeneration, more reps before failure, more total training volume. Volume is the primary driver of hypertrophy. More volume means more growth over time.

But creatine does more than enhance performance. It draws water into muscle cells, creating a more anabolic environment. Cell swelling itself stimulates protein synthesis. Your muscles look fuller and function better when adequately hydrated at the cellular level.

Research also demonstrates cognitive benefits. The brain uses significant ATP, especially during demanding tasks. Creatine supplementation improves mental performance under stress, sleep deprivation, and cognitive load. It may provide neuroprotective effects as well.

The myths about creatine are persistent but false. It does not damage kidneys in healthy individuals. It is not a steroid. It does not cause hair loss. The water retention is intracellular, not the bloated subcutaneous kind. These concerns have been addressed repeatedly in clinical research.

The Protocol

1. **Use creatine monohydrate**: This is the most researched form. Fancy versions like creatine HCL or buffered creatine offer no advantage despite higher prices. Plain monohydrate works.

2. **Take 3-5 grams daily**: Consistency matters more than timing. Some people take it pre-workout, some post-workout, some with breakfast. It does not matter. Just take it every day.

3. **Skip the loading phase**: Traditional protocols suggest 20g daily for a week to saturate stores faster. This is unnecessary and often causes GI distress. Taking 5g daily reaches saturation within 3-4 weeks without the side effects.

4. **Dissolve in warm liquid**: Creatine dissolves poorly in cold water. Warm water, coffee, or tea improves solubility. Undissolved creatine can cause stomach issues.

5. **No cycling required**: Creatine does not suppress natural production. You do not need to cycle off. Continuous use is fine and maintains saturated stores.

6. **Combine with carbohydrates**: Insulin enhances creatine uptake into muscles. Taking creatine with a carbohydrate-containing meal improves absorption. This is optimization, not necessity.

7. **Stay hydrated**: Creatine increases intramuscular water retention. Your overall fluid needs increase slightly. Drink according to thirst.

If you train with any intensity and you are not taking creatine, you are leaving gains on the table. It is the single most validated supplement for performance and body composition. Start taking it.