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Science12/13/202510 min read

Protein Timing vs. Total Intake: Debunking the Anabolic Window

Still chugging a lukewarm shake in the locker room because you're terrified of losing gains? Relax mate. The science says you've got way more time than you think.

We've all seen it. The bloke in the change room, towel barely on, shaking his shaker cup like his life depends on it. He's stressed, he's frantic, because he's been told that if he doesn't get 30g of whey isolate into his system within 20 minutes of his last set, his muscles will shrivel up and fall off.

This is the myth of the 'Anabolic Window'. And like most bro-science, it's based on a grain of truth that's been blown massively out of proportion.

Muscle Protein Synthesis (MPS) 101

To build muscle, your body needs to be in a state of positive nitrogen balance. You need simply: Muscle Protein Synthesis (building) > Muscle Protein Breakdown (destroying).

Resistance training triggers MPS. Eating protein triggers MPS. The theory was that you needed to 'stack' these triggers immediately to get maximum growth. But the human body isn't that fragile.

The Window is a Barn Door

Research over the last decade has pretty conclusively shown that the 'anabolic window' lasts significantly longer than 30 minutes. In fact, for most trained individuals, the sensitising effect of a workout on your muscles can last 24-48 hours.

Unless you haven't eaten for 12 hours before your workout (training completely fasted), your body still has amino acids circulating in the bloodstream from your last meal. There is no emergency.

Hierarchy of Importance

If we look at what actually drives hypertrophy, the hierarchy is clear:

1. Total Daily Protein Intake (The King)

Hitting roughly 1.6g to 2.2g of protein per kg of body weight is the most critical factor. If you nail this, timing becomes a minor detail. If you fail this, no amount of post-workout shakes will save you.

2. Protein Quality (Leucine Threshold)

Not all proteins are created equal. You need essential amino acids, specifically Leucine, to 'switch on' the muscle building machinery (mTOR). Animal products, whey, and properly combined plant sources are best here.

3. Protein Distribution

While the window isn't 30 mins, eating 200g of protein in one meal isn't optimal either. Spreading your intake across 3-5 meals optimises the 'spikes' of MPS throughout the day.

When Timing Actually Matters

I'm not saying timing is useless. If you're an elite athlete training two-a-days (training twice in one day), then yes, slamming carbs and protein immediately after Session 1 is crucial to replenish glycogen for Session 2.

But for 99% of us just trying to look good naked? It doesn't matter. Go home, have a shower, cook a proper meal with whole foods. Your muscles will be there waiting for you.